Founded in 2017

About

The mission of A.I. VALI is to improve patient care by empowering healthcare providers, pharma/biotech, and researchers, with high-precision AI capabilities, more accurately identifying diseases such as cancer, and improve the economy of the clinics or clinical trials. A.I. VALI has developed a versatile AI platform (AIDREA™) that uses interactive machine learning and deep learning technologies to document and analyze endoscopy video images in real-time to facilitate accurate reporting, diagnosis and quality-based clinical practice. AIDREA™ enables real-time annotation of images and immediate, post-procedural generation of a standardized endoscopy report.

McMaster Founders

David Armstrong (Faculty Health Sciences).

  A.I. VALI Homepage

Founded in 2015

About

Acuity Insights (formerly Altus) delivers assessments focused on non-cognitive aspects of trainees,  program management and data analytics solutions specifically for higher education. The HigherEd Intelligence platform provides tools and data needed to run great programs and train even better professionals. Acuity began with an assessment for medical school applicants, they have since expanded their assessments to both other health professions and higher education. Their initial product, Casper – Computer-Based Assessment for Sampling Personal Characteristics – is written by over 95% of applicants to US and Canadian medical schools, and more than 80% of applicants for Canadian medical residency programs.

McMaster Founders

Kelly Dore and Harold Reiter (Faculty Health Sciences).

  Acuity Insights Homepage

Founded in 2016

About

Adapsyn is a biotechnology company focused on the identification and characterization of microorganism-derived small molecules to uncover chemical agents possessing novel biological activities relevant to the biotechnology and pharmaceutical sectors. Adapsyn technology drives the discovery of a diversified portfolio of drugs, thereby expediting the search for medicines that will better protect users from a wide spectrum of diseases.

McMaster Founder

Nathan Magarvey (Faculty of Health Sciences).

  Adapsyn Homepage

Founded in 2021

About

Afynia Laboratories Inc. is a pre-clinical FemTech Biotechnology company co-founded by two scientists who have dedicated their professional lives to researching reproductive endocrinology and infertility. Their goal is to develop new products to fill current gaps in women’s health. Formerly known as AIMA.

McMaster Founders

Lauren Foster and Jocelyn Wessels (Faculty of Health Sciences).

  Afynia Laboratories Homepage

Founded in 2019

About

Allarta Life Science is a pre-clinical regenerative medicine company with a proprietary allogeneic cell delivery platform to enable cell-based, curative therapies for chronic endocrine disorders such as Diabetes, Hemophilia and Lysosomal Storage Disorders, without the need for immune suppression.

McMaster Founder

Harald Stover (Faculty of Science).

  Allarta Life Science Homepage

Founded in 2024

About

BiCova is an early stage company developing the Covalent Bifunctional Molecules (CBM) platform. CBMs are proximity inducing molecules that have the capability for activation and targeting of immune cells toward cancers and other disease tissue, as well as enable and enhance protein target inhibition or degradation. Candidates from the CBM platform have superior activity by creating covalent linkages to targets rather than competitive binding and have shown to have significantly higher efficacy at lower dosages. Because of the unique chemistry used, CBMs can be constructed from existing ligands with low micromolar or high nanomolar binding, converting these to covalent binders with high specificity. The company is developing two programs internally; CBMs against uPAR and Her2 tumours and the inhibition / degradation of TNFa in Rheumatoid arthritis. The company’s platform is well suited for partnering with pharma in several areas..

McMaster Founder

Anthony Rullo (Faculty Health Sciences).

  BiCova Therapeutics Homepage

Founded in 2019

About

Elarex is developing next generation vaccine platforms to address emerging infectious diseases and commercial vaccine targets.

McMaster Founder

Carlos Filipe (Faculty Engineering).

  Elarex Homepage

Founded in 2015

About

Enedym is a transportation electrification technology company enabling better motors to be designed and built faster. The company’s vision is to cut the cost of electric propulsion motors significantly and power a new paradigm in the electric motor industry through novel switched reluctance motor (SRM) drive technologies.

McMaster Founders

Ali Emadi and Berker Bilgin (Faculty of Engineering).

  Enedym Homepage

Founded in 2023

About

Esphera SynBio has a platform technology allowing for the generation of designer exosomes, either in vivo or ex vivo. These engineered exosomes can be targeted to specific cells in the body to deliver a defined payload or payloads. This is achieved through the expression of transgenes in a producer cell leading to the production of multimeric proteins that accumulate in budding exosomes. There is great flexibility in the nature of the cells that can be targeted (tumour cells, immune cells, etc.) and the therapeutic payloads loaded, including enzymes (toxic, immune-stimulatory, replacement), as well as RNAs (miRNA, siRNA, mRNA or self-replicating RNAs). Esphera focuses on applying this technology to the treatment of infectious diseases and cancer.

McMaster Founder

Brian Lichty (Faculty Health Sciences).

Founded in 2014

About

Evidence Prime creates modern IT collaboration tools for Evidence-Based Health Care experts, allowing them to streamline the process of health care decision making. For example, GRADEpro tool and laserai.

McMaster Founders

Jan Brozek and Holger Schünemann (Faculty of Health Sciences).

  Evidence Prime Homepage

Founded in 2013

About

Exerkine Corporation is a nutra-pharmaceutical company that is developing a new class of therapies to treat acquired and genetic disorders. Recent advances in mitochondrial sciences, exercise physiology, and nutrition are fueling innovation in exerkine-based therapies. A passion for health and fitness drives their pre-clinical and clinical R&D pipeline, while their business focus is on commercializing and leveraging intellectual property. Exerkine’s commitment is to commercialize products that are truly built and backed by science.

McMaster Founder

Mark Tarnopolsky (Faculty of Health Sciences).

  Exerkine Homepage

Founded in 2020

About

FendX Technologies Inc. is a technology company focused on developing surface protection products that protect surfaces from pathogen contamination.

McMaster Founders

Leyla Soleymani and Tohid Didar (Faculty of Engineering).

  FendX Technologies Homepage

Founded in 2014

About

Fusion Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on becoming the leader in the Targeted Alpha Therapy field. It is a spinout of the Centre for Probe Development and Commercialization (CPDC), a leading radiopharmaceutical research and GMP production centre headquartered at McMaster University. Their Targeted Alpha Therapy has the potential to be used across multiple tumor types including colorectal, bladder, lung cancer and more.

McMaster Founder

John Valliant (Faculty of Science).

  Fusion Pharmaceuticals Homepage

Founded in 2018

About

HARvEST Systems utilized a collaborative research initiative between Pizza Pizza Limited, Thermal Electronics Corporation, and McMaster University for the development of the POWER system. It is a technological solution that improves the overall energy utilization of restaurants ultimately reducing operating costs, minimizing greenhouse gas production, and providing electrical resiliency during power outages.

McMaster Founder

James Cotton (Faculty of Engineering).

  Harvest Systems Homepage

Founded in 2018

About

MesoMat provides high-resolution, real time sensing data to help tire OEMs, performance races, and industrial manufacturers improve product performance & design, unlock operation efficiencies, and innovate new revenue models.

McMaster Founders

Kari Dalnoki-Veress, Paul Fowler, and Sukhbir Kalirai (Faculty of Science).

  MesoMat Homepage

Founded in 2021

About

Naturally Synthetic aims to realize the full potential of a new synthetic chemistry technology. Many plant-derived molecules can be made available in large quantities and high purity. This opens the door to their clinical testing and potential approval as medicines or nutraceuticals to improve human health and wellbeing.

McMaster Founder

Jakob Magolan (Faculty of Science).

  Naturally Synthetic Homepage

Founded in 2021

About

OrganoBiotech offers a core product, IFlowPlate, that allows users to produce a variety of complex preclinical models for high-throughputs precision drug screening. Specifically, IFlowPlate enhances existing tissue and organoid cultures with perfusabe blood vessels and optimized micro-environment.

McMaster Founders

Boyang Zhang, Dawn Lin, and Shravanthi Rajasekar (Faculty of Engineering).

  Organo Biotech Homepage

Founded in 2004

About

ProSensus provides consulting services, turn-key machine vision solutions, and educational opportunities related to the application of advanced analytics for manufacturing in product development, process troubleshooting & optimization, and quality control across the chemicals & oil & gas, pharmaceutical, food & beverage, and rubber industries.

McMaster Founder

John MacGregor (Faculty of Engineering).

  ProSensus Homepage

Founded in 2008

About

ProspectHR MMI is in the soft skills assessment business. The company has databank of interview scenarios (now over 600) and markets two products in three industry verticals: academic institutions, government, and businesses. The core client segment continues to be medical schools in the US.

McMaster Founders

Jack Rosenfeld and Harold Reiter (Faculty of Health Sciences).

  ProspectHR MMI Homepage

Founded in 2019

About

PROVA specializes in wearable technology solutions for in-home GAIT training and neuromuscular rehabilitation for patients with a brain injury, neurological disorder, degenerative disease, or a mobility challenge.

McMaster Founder

Matthew Rosato (P.Eng, MBA)

  PROVA Innovations Homepage

Founded in 2014

About

QReserve helps organizations with complex scheduling workflows to automate and optimize their processes through a powerful online web platform, integrations, and expert support.

McMaster Contributors

John Brennan, Fred Capretta and Brandon Aubie (Faculty of Science).

  QReserve Homepage

Founded in 2020

About

Synmedix is a biotechnology company that dramatically enhances the effectiveness of antibiotics to address unmet medical need posed by the global health crisis in antibiotic resistance. Synmedix is developing new antibiotic therapies for treating critical infections, with a lead candidate entering clinical trials as a first-in-class therapy to treat infections associated with diabetic foot ulcers.

McMaster Founders

Eric Brown and Geordie Stewart (Faculty of Health Sciences).

  Learn more about Synmedix

Founded in 2020

About

Synth-Med Biotechnology makes blood smart by producing functional red blood cells as part of a proprietary platform that delivers drugs to specific targets of 3 main areas: erythrocyte-based nutraceuticals, functionalized erythrocytes for the delivery of cancer vaccines, and delivering neurotrophic factor across the blood-brain barrier.

McMaster Founders

Maikel Rheinstadter and Sebastian Himbert (Faculty of Science).

  Synth-Med Biotechnology Homepage

Founded in 2018

About

TBIFinder is a biomedical data analytics company, that locates and grades impaired brain regions via advanced MRI analytics to help better understand, differentiate and communicate complex symptom presentations, while providing opportunity for more efficient personalized treatment approaches.

McMaster Founders

Michael Noseworthy, Nicholas Simard and Dinesh Khumbare (Faculty of Engineering, Faculty of Health Sciences).

  TBIFinder Homepage

Founded in 2009

About

Trillium Meditec is developing and commercializing novel products utilizing hydrogel technologies to treat conditions with currently inadequate therapies.

McMaster Founder

Todd Hoare (Faculty of Engineering).

  Trillium Meditec Homepage

Founded in 2015

About

Triumvira is a clinical-stage immuno-oncology company, anchored in a deep understanding of T cell biology. They are developing unique, targeted autologous and allogeneic T cell therapeutics that co-opt the natural biology of T cells to treat a broad range of patients with cancer.

McMaster Founder

Jonathan Bramson (Faculty of Health Sciences).

  Triumvira Homepage

Founded in 2014

About

Turnstone Biologics is a clinical stage biotechnology company developing new medicines to treat and cure solid tumors by pioneering a differentiated approach with tumor-infiltrating lymphocyte (TIL) therapy. Solid tumors represent the most critical unmet need in oncology. To overcome this barrier, Turnstone is developing next-generation TIL therapies based on the identification, selection, and expansion of the most potent tumor-reactive T-cells.

McMaster Founder

Brian Lichty (Faculty of Health Sciences).

  Turnstone Biologics Homepage

Founded in 2017

About

VoxNeuro develops reliable, accessible, leading-edge EEG-based brain performance software. They support clinician expertise and enable them to expand their influence while participating in the economics of the growing cognitive brain health market.

McMaster Founder

John Connolly (Faculty of Humanities).

  VoxNeuro Homepage