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Ontario Institute for Cancer Research: Cancer Therapeutics Innovation Pipeline

Research Admin Offices:

  • ROADS
  • HRS

Funding Type:

Grant

Opportunity Type:

  • Grant

Value:

Funding varies by program, $150,000 over one year – $500,000 over two years.

Disciplines:

  • Health Sciences

Sponsors:

Deadlines:

Internal Deadline:

April 19, 2023

Sponsor Deadline:

May 3, 2023

Additional Dates:

  • NOI & LOI HRS Due Date - April 19, 2023
  • NOI & LOI Sponsor Due Date - May 3, 2023
  • Application Sponsor Due Date (by invitation) - August 2, 2023

Description:

CTIP will support projects that aim to provide increasing evidence of target validation and disease association using data from knowledgebases, functional assays, and drug screening in relevant in vitro and in vivo models of the cancer type of interest.

  • Early Validation projects: Deliver robust translational evidence that a Target-of-Interest (TOI) is associated to a specific cancer type based on data from knowledge bases and from studies demonstrating that perturbation of the TOI in relevant cell-based or higher order models produces anti-cancer effects sufficient to trigger a drug discovery campaign.
  • Early Accelerator projects: Deliver a validated primary assay to enable initial screening of molecules against a defined target. Preliminary evidence of linearity of results between the primary assay and supporting secondary assays under development is also required.
  • Late Accelerator projects: Deliver confirmed Hit molecules against a defined target using validated primary, secondary and orthogonal assays for screening.

Additional Program Information:

Program Information Webinar: April 18, 2023, from 2:00 pm to 3:00 pm.

Resources:

Additional Details.

Contact:

If applying from the Faculty of Health Sciences, unless otherwise indicated, you no longer need to send documents to HRS Intake. Your first point of contact is your assigned Senior Grants Advisor.

ROADS: For more information and to apply, contact Beatrice Fletcher, Senior Advisor.